Thioredoxin has also been demonstrated to bind to ASK1 to inhibit its activity as being a kinase [32]. This inhibition is attenuated by ROS that can result in dimerization of thioredoxin [33]. Thioredoxin regulation with the glucocorticoid receptor by Affiliation for the DNA binding area has also been noted [34] and this too is motivated by ROS. Ad

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